HUCOG 5000 HCG Injection 5000iu Bharat serums Pack of 3

$57.32

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  • HUCOG 5000 HCG Injection 5000iu Bharat serums Pack of 3

    $57.32

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    •   Size Guide

      Quantity Guide

      ITEMS GRAMS KILOGRAMS
      1 34 28 34
      2 36 30 36
      3 38 32 38
      4 40 34 40
      5 42 36 42
      100 44 38 44

      All measurements are in GRAMS

      and may vary a half gram in either direction.

       
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      HUCOG 5000 HCG Injection 5000iu Bharat serums Pack of 3

      $57.32

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      HUCOG 5000IU is widely known as Novarel, Ovidrel, Pregnyl, Human chorionic gonadotropin, hCG

      Other alternative names for

      3 x 5000IU

       (hCG): Bharat Serums, hCG, Human Chorionic Gonadotropin, hCG, Human Chorionic Gonadotropin, Novarel , HUCOG 

      3 x 5000IU


      All of these are different brands of the same active substance – hCG

      Highly Purified Chorionic Gonadotrophin Injection HUCOG®

       
      For Subcutaneous / Intramuscular Injection only
       
      Composition :
      Each ml contains :
      2000 I.U. / 5000 I.U. / 10000 I.U.
      Water for Injection I.P
      q.s.
      Excipients & Stabilizers :
      Disodium Hydrogen Phosphate Dihydrate I.P., Benzyl Alcohol I.P., Sucrose I.P., Poloxamer
      188
      U.S.P./NF, Methionine B.P., Phosphoric acid I.P.
      One IU of Chorionic Gonadotrophin is defined as the activity contained in 1.279 mg of the 2nd International
      Standard Preparation.
      Properties :
      Chorionic Gonadotrophin (HCG) is a hormonal substance obtained from urine of pregnant women. Its
      action is predominantly luteinizing.
       
      Indications :
      Anovulatory infertility :
      In the female, HUCOG HP is used in the treatment of anovulatory infertility. where its administration would
      form part of recognized treatment regimen involving prior stimulation of follicular maturation and
      endometrial proliferation e.q. with Menotropin Injection (HUMOG HP).
      Hypogonadotrophin hypogonadism and cryptorchidism :
      In the male, HUCOG HP stimulates the interstitial cells of the testes and consequently the secretion of
      androgens and the development of secondary sexual characteristics. With concomitant Menotropin
      Injection therapy, HUCOG HP stimulates the induction and maintenance of spermatogenesis.
       
      Dosage and Administration :
      HUCOG HP is given by subcutaneous / intramuscular injection only.
      Anovulatory infertility :
      HUCOG HP 10000 I.U. is administered in mid-cycle, following treatment with Menotropin Inj. (HUMOG HP)
      according to a recognised scheme. Details of Menotropin Inj. (HUMOG HP) dosage and monitoring are
      available on request.
      Hypogonadotrophic hypogonadism :
      HUCOG HP 2000 I.U. twice weekly concomitant with Menotropin Inj. (HUMOG HP) (1 vial three times a
      week) if necessary for a minimum period of four months.
       
      Cryptorchidism :
      Equivalent to 1000 I.U. of HUCOG HP on alternate days for several weeks.
      Contra-Indication and Warnings :
      Stimulation of ovulation with HUCOG HP may lead to superovulation and the hyperstimulation syndrome.
      Oestrogen assays will detect the excessive response so that HUCOG HP (HCG) may be withheld in that
      particular treatment cycle. In the male, high dosages of HUCOG HP may lead to oedema and in such
      cases dosages should be considerably reduced.
      If signs of sexual precocity are observed a reduced dosage regimen should be instituted.
       
      Side Effects :
      Headache, irritability, restlessness, depression, fatigue, edema, gynecomastia, sexual precocity, pain at
      the site of injection.
       
      Adverse Events :
      The adverse reactions for use in infertility are: (1) Ovarian hyperstimulation (OHSS), a syndrome of
      sudden ovarian enlargement, ascites with or without pain, and/or pleural effusion, (2) Rupture of ovarian
      cysts with resultant hemoperitoneum, (3) Multiple births, and (4) Arterial thrombo-embolism.
       
      PRECAUTION :
      HCG should be used in conjunction with human menopausal gonadotropins only by physicians
      experienced with infertility problems who are familiar with the criteria for patient selection,
      contraindications, warnings, precautions, and adverse reactions described in the package insert for
      menotropins.
      Interaction with other medicinal products and other forms of interaction :
      Concomitant use of HuCoG Injection with other agents used to stimulate ovulation
      (e.g. HMG,
      clomiphene citrate) may potentiate the follicular response. (See Warnings Precaution & Overdosage.)
      Overdose :
      The effects of an overdose of HuCoG Injection are unknown, nevertheless one could expect ovarian
      hyperstimulation syndrome (OHSS) to occur, which is further described as below:
      Ovarian Hyperstimulation Syndrome (OHSS) : (See Warnings) :
      OHSS is a medical event distinct from uncomplicated ovarian enlargement. OHSS is a syndrome that can
      manifest itself with increasing degrees of severity. It comprises marked ovarian enlargement, high serum
      sex steroids, and an increase in vascular permeability which can result in an accumulation of fluid in the
      peritoneal, pleural and, rarely, in the pericardial cavities.
      The following symptomatology may be observed in severe cases of OHSS : abdominal pain,
      abdominal distension, severe ovarian enlargement, weight gain, dyspnoea, oliguria and gastrointestinal
      symptoms including nausea, vomiting and diarrhoea.
      Adherence to recommended HuCoG Injection dosage, regimen of administration and careful monitoring
      of therapy will minimize the incidence of ovarian hyper stimulation and multiple gestations. In ART,
      aspiration of all follicles prior to ovulation may reduce the occurrence of hyper stimulation. OHSS may be
      more severe and more protracted if pregnancy occurs. Most often, OHSS occurs after hormonal treatment
      has been discontinued and reaches its maximum at about seven to ten days following treatment. Usually,
      OHSS resolves spontaneously with the onset of menses. If severe OHSS occurs, gonadotrophin treatment
      should be stopped if still ongoing, the patient hospitalized and specific therapy for OHSS started. This
      syndrome occurs with higher incidence in patients with polycystic ovarian disease.
      Ovarian response should be carefully monitored to minimize the risk of overstimulation. If the ovaries are
      abnormally enlarged on last day of gonadotrophin therapy, HCG should not to be administered in this
      course therapy. This reduces development of OHSS (Ovarian Hyperstimulation Syndrome). Use of
      ultrasound monitoring of ovarian response and/or measurement of serum estradiol levels can further
      minimize the risk of overstimulation.
      Storage :
      Vials of HUCOG HP should be stored between 20C – 80C. Do not freeze. Protect from light. Any unused
      portion should be discarded.
       
      Presentation :
      HUCOG HP is supplied in vials containing sterile having activity of 2000 I.U. / 5000 I.U. / 10000 I.U.
      Manufactured in India by :
      BHARAT SERUMS AND VACCINES LIMITED

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