Ipamorelin 5mg by Knoll


  • Ipamorelin 5mg by Knoll


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    •   Size Guide

      Quantity Guide

      1 34 28 34
      2 36 30 36
      3 38 32 38
      4 40 34 40
      5 42 36 42
      100 44 38 44

      All measurements are in GRAMS

      and may vary a half gram in either direction.

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      Ipamorelin 5mg by Knoll


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      What is Ipamorelin:
      Ipamorelin is a peptide agonist of the Ghrelin Hormone Secretagogue Receptor (GHSR), which significantly increases plasma growth hormone (GH) levels in humans. The pharmaceutical company Novo Nordisk originally developed this peptide, but now it has been discontinued because of its low effectiveness. It was tended to be used for the stimulation of growth of children with growth retardation.
      How does it work?
      Ipamorelin binds of GHSR due to its agonist property to activate it in the search for a biological response. This receptor is located in the hypothalamic ventromedial nucleus of the brain and it is in charge of the production of energy homeostasis (that enhance the regulation of caloric intake by signaling the brain to regulate the sensation of hunger) and the regulation of body weight.
      Results and benefits:
      Unlike other peptides, Ipamorelin does not affect prolactin, which is a protein secreted by the pituitary gland in response to eating, mating, estrogen treatment, ovulation, and nursing. It enables the production milk of mammals and it regulates the immune system as well as the pancreatic development.
      No adverse effects have been reported both in Follicle-Stimulating Hormone (FSH) as in Luteinizing hormone (LH). FSH and LH cause the release of ovulation through the stimulation of the ovaries in women, and they contribute to produce testosterone and sperm through the stimulation of the testicles in men.
      No effect has been reported Thyroid-Stimulating Hormone (TSH) during the use of Ipamorelin. This is important because TSH plays an important role in the stimulation of the metabolism of almost every tissue in the body; it regulates the endocrine function of the thyroid that stabilizes the level of thyroid hormones avoiding an excessive production that can cause hyperthyroidism and the deficiency of the same hormones leading to hypothyroidism.
      Ipamorelin does not stimulate the secretion of Adrenocorticotropic Hormone (ACTH) that is produced on the anterior pituitary gland. ACTH is stimulated by biological stress and can increase the production of cortisol (depressing the immune system). Elevated ACTH levels could be caused by adrenal insufficiency, which is a lack of production of adequate amounts of steroid hormones like cortisol.
      There are no reports of cortisol affections caused by Ipamorelin. As it mentioned above cortisol is in charge of maintaining an adequate balance of the insulin by keeping optimal levels of sugar in the blood, as well as the use of sugar and fat to obtain energy. It also contributes to control and respond to stress (people suffering chronic stress and depression has shown high levels of cortisol). Cortisol regulates the blood pressure (avoiding alterations to the heart, the kidney, the vision, the sexual performance, the memory, and the arterial function) and the immune system.
      Ipamorelin dosage:
      The average dosing for Ipamorelin is 200-300mcg two to three times daily. Twelve-week cycles are quite normal.

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